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Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome

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Science Immunology  07 Oct 2016:
Vol. 1, Issue 4, eaah3732
DOI: 10.1126/sciimmunol.aah3732

Article Information

vol. 1 no. 4

PubMed: 
Published By: 
History: 
  • Received June 17, 2016
  • Accepted September 6, 2016

Author Information

  1. Julien Zuber1,2,
  2. Brittany Shonts1,*,
  3. Sai-Ping Lau1,*,
  4. Aleksandar Obradovic1,
  5. Jianing Fu1,2,
  6. Suxiao Yang1,2,
  7. Marion Lambert3,
  8. Shana Coley1,4,
  9. Joshua Weiner1,5,
  10. Joseph Thome1,6,
  11. Susan DeWolf1,2,
  12. Donna L. Farber1,5,6,
  13. Yufeng Shen7,
  14. Sophie Caillat-Zucman3,
  15. Govind Bhagat4,
  16. Adam Griesemer1,5,
  17. Mercedes Martinez8,
  18. Tomoaki Kato5 and
  19. Megan Sykes1,2,5,6,
  1. 1Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY 10032, USA.
  2. 2Department of Medicine, Columbia University, New York, NY 10032, USA.
  3. 3INSERM UMR1149, Hôpital Robert-Debré, Paris, France.
  4. 4Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA.
  5. 5Department of Surgery, Columbia University, New York, NY 10032, USA.
  6. 6Department of Microbiology & Immunology, Columbia University, New York, NY 10032, USA.
  7. 7Center for Computational Biology and Bioinformatics, Columbia University Medical Center, New York, NY 10032, USA.
  8. 8Department of Pediatrics, Columbia University, New York, NY 10032, USA.
  1. Corresponding author. Email: megan.sykes{at}columbia.edu
  1. * These authors contributed equally to this work.

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