Research ArticleINFECTIOUS DISEASES
Interferon-driven deletion of antiviral B cells at the onset of chronic infection
- Benedict Fallet1,*,
- Kerstin Narr1,*,
- Yusuf I. Ertuna1,
- Melissa Remy1,
- Rami Sommerstein2,
- Karen Cornille1,
- Mario Kreutzfeldt2,3,
- Nicolas Page2,
- Gert Zimmer4,
- Florian Geier5,
- Tobias Straub6,
- Hanspeter Pircher6,
- Kevin Larimore7,8,
- Philip D. Greenberg7,8,
- Doron Merkler2,3 and
- Daniel D. Pinschewer1,†
- 1Division of Experimental Virology, Department of Biomedicine, University of Basel, 4003 Basel, Switzerland.
- 2Department of Pathology and Immunology, Geneva Faculty of Medicine, Geneva University Hospital, 1211 Geneva 4, Switzerland.
- 3Division of Clinical Pathology, Geneva University Hospital, 1 rue Michel Servet, 1211 Geneva 4, Switzerland.
- 4Institute of Virology and Immunology, 3147 Mittelhäusern, Switzerland.
- 5Department of Biomedicine, Bioinformatics Core Facility, University Hospital Basel, 4031 Basel, Switzerland.
- 6Department for Medical Microbiology and Hygiene, Institute for Immunology, University Medical Center Freiburg, 79104 Freiburg, Germany.
- 7Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA.
- 8Department of Immunology, University of Washington, Seattle, WA 98109, USA.
- ↵†Corresponding author. Email: daniel.pinschewer{at}unibas.ch
↵* These authors contributed equally to this work.
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Science Immunology 21 Oct 2016:
Vol. 1, Issue 4, eaah6817
DOI: 10.1126/sciimmunol.aah6817
