Research ArticleCANCER IMMUNOLOGY

Intratumoral delivery of inactivated modified vaccinia virus Ankara (iMVA) induces systemic antitumor immunity via STING and Batf3-dependent dendritic cells

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Science Immunology  19 May 2017:
Vol. 2, Issue 11, eaal1713
DOI: 10.1126/sciimmunol.aal1713

Article Information

vol. 2 no. 11

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History: 
  • Received October 7, 2016
  • Accepted April 7, 2017

Author Information

  1. Peihong Dai1,2,*,
  2. Weiyi Wang1,*,
  3. Ning Yang1,
  4. Cristian Serna-Tamayo1,
  5. Jacob M. Ricca3,
  6. Dmitriy Zamarin3,4,5,6,
  7. Stewart Shuman2,
  8. Taha Merghoub3,4,5,
  9. Jedd D. Wolchok3,4,5,6 and
  10. Liang Deng1,6,
  1. 1Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  2. 2Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  3. 3Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  4. 4Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  5. 5Melanoma and Immunotherapeutics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  6. 6Weill Cornell Medical and Graduate Colleges, New York, NY 10065, USA.
  1. Corresponding author. Email: dengl{at}mskcc.org
  1. * These authors contributed equally to this work.

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