Research ArticleIMMUNE REGULATION

Tfr cells lack IL-2Rα but express decoy IL-1R2 and IL-1Ra and suppress the IL-1–dependent activation of Tfh cells

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Science Immunology  08 Sep 2017:
Vol. 2, Issue 15, eaan0368
DOI: 10.1126/sciimmunol.aan0368

Article Information

vol. 2 no. 15

PubMed: 
Published By: 
History: 
  • Received February 24, 2017
  • Revision received May 26, 2017
  • Accepted July 19, 2017

Author Information

  1. Paul-Gydeon G. Ritvo1,
  2. Guillame Churlaud1,2,
  3. Valentin Quiniou1,2,
  4. Laura Florez1,
  5. Faustine Brimaud1,
  6. Gwladys Fourcade1,
  7. Encarnita Mariotti-Ferrandiz1 and
  8. David Klatzmann1,2,*
  1. 1Sorbonne Université, University Pierre and Marie Curie (UPMC), Univ Paris 06, INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (i3), F-75005 Paris, France.
  2. 2AP-HP (Assistance Publique–Hôpitaux de Paris), Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi), and Inflammation-Immunopathology-Biotherapy Department (i2B), F-75651 Paris, France.
  1. *Corresponding author. Email: david.klatzmann{at}upmc.fr

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