Research ArticleAUTOIMMUNITY

LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes

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Science Immunology  31 Mar 2017:
Vol. 2, Issue 9, eaah4569
DOI: 10.1126/sciimmunol.aah4569

Article Information

vol. 2 no. 9

Published By: 
History: 
  • Received June 29, 2016
  • Revision received December 18, 2016
  • Accepted February 14, 2017

Author Information

  1. Qianxia Zhang1,2,
  2. Maria Chikina3,
  3. Andrea L. Szymczak-Workman1,2,
  4. William Horne4,
  5. Jay K. Kolls4,
  6. Kate M. Vignali1,2,
  7. Daniel Normolle5,
  8. Maria Bettini2,*,
  9. Creg J. Workman1,2 and
  10. Dario A. A. Vignali1,2,6,
  1. 1Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  2. 2Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA.
  3. 3Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  4. 4Richard King Mellon Foundation Institute for Pediatric Research, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA.
  5. 5Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA 15232, USA.
  6. 6Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA.
  1. Corresponding author. Email: dvignali{at}pitt.edu
  • * Present address: Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

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