Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis

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Science Immunology  19 Jan 2018:
Vol. 3, Issue 19, eaan8664
DOI: 10.1126/sciimmunol.aan8664

Article Information

vol. 3 no. 19

Published By: 
  • Received May 30, 2017
  • Revision received September 27, 2017
  • Accepted November 30, 2017

Author Information

  1. Veena S. Patil1,
  2. Ariel Madrigal1,
  3. Benjamin J. Schmiedel1,
  4. James Clarke1,2,
  5. Patrick O’Rourke1,
  6. Aruna D. de Silva1,3,*,
  7. Eva Harris4,
  8. Bjoern Peters1,5,
  9. Gregory Seumois1,
  10. Daniela Weiskopf1,
  11. Alessandro Sette1,5 and
  12. Pandurangan Vijayanand1,5,6,
  1. 1Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
  2. 2Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
  3. 3Genetech Research Institute, Colombo, Sri Lanka.
  4. 4Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.
  5. 5Department of Medicine, University of California San Diego, 9500 Gilman Drive #0656, La Jolla, CA 92093, USA.
  6. 6Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, Faculty of Medicine University of Southampton, Southampton, UK.
  1. Corresponding author. Email: vijay{at}
  • * Present address: Department of Paraclinical Sciences, Faculty of Medicine, Kotelawala Defense University, Ratmalana, Sri Lanka.


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