RORα-expressing T regulatory cells restrain allergic skin inflammation

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Science Immunology  02 Mar 2018:
Vol. 3, Issue 21, eaao6923
DOI: 10.1126/sciimmunol.aao6923

Article Information

vol. 3 no. 21

Published By: 
  • Received August 16, 2017
  • Accepted January 17, 2018

Author Information

  1. Nidhi Malhotra1,*,,,
  2. Juan Manuel Leyva-Castillo1,*,,
  3. Unmesh Jadhav2,3,
  4. Olga Barreiro4,
  5. Christy Kam1,
  6. Nicholas K. O’Neill2,3,
  7. Francoise Meylan5,
  8. Pierre Chambon6,
  9. Ulrich H. von Andrian4,
  10. Richard M. Siegel5,
  11. Eddie C. Wang7,
  12. Ramesh Shivdasani2,3 and
  13. Raif S. Geha1,
  1. 1Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  2. 2Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  3. 3Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  4. 4Department of Microbiology and Immunobiology and Center for Immune Imaging, Harvard Medical School, Boston, MA 02115, USA.
  5. 5Immunoregulation Section, Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  6. 6Institut de Génétique et de Biologie Moléculaire et Cellulaire (CNRS UMR7104, INSERM U964), Illkirch 67404, France.
  7. 7Department of Microbial Microbiology and Infectious Diseases, School of Medicine, Cardiff University, Cardiff, UK.
  1. Corresponding author. Email: nidhi.malhotra{at} (N.M.); manuel.leyvacastillo{at} (J.M.L.-C.); raif.geha{at} (R.S.G.)
  1. * These authors contributed equally to this work.

  • Present address: Elstar Therapeutics, 840 Memorial Drive, Cambridge, MA 02139, USA.


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