Research ArticleCANCER IMMUNOLOGY

Combination cancer immunotherapy targeting PD-1 and GITR can rescue CD8+ T cell dysfunction and maintain memory phenotype

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Science Immunology  02 Nov 2018:
Vol. 3, Issue 29, eaat7061
DOI: 10.1126/sciimmunol.aat7061

Article Information

vol. 3 no. 29

PubMed: 
Published By: 
History: 
  • Received March 26, 2018
  • Accepted October 11, 2018

Author Information

  1. Bei Wang*,
  2. Wen Zhang*,
  3. Vladimir Jankovic,
  4. Jacquelynn Golubov,
  5. Patrick Poon,
  6. Erin M. Oswald,
  7. Cagan Gurer,
  8. Joyce Wei,
  9. Ilyssa Ramos,
  10. Qi Wu,
  11. Janelle Waite,
  12. Min Ni,
  13. Christina Adler,
  14. Yi Wei,
  15. Lynn Macdonald,
  16. Tracey Rowlands,
  17. Susannah Brydges,
  18. Jean Siao,
  19. William Poueymirou,
  20. Douglas MacDonald,
  21. George D. Yancopoulos,
  22. Matthew A. Sleeman,
  23. Andrew J. Murphy and
  24. Dimitris Skokos
  1. Regeneron Pharmaceuticals,Tarrytown, New York, NY 10591, USA.
  1. Corresponding author. Email: dimitris.skokos{at}regeneron.com
    • * These authors contributed equally to this work.

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