Single-cell transcriptional analysis reveals ILC-like cells in zebrafish

Pedro P. Hernández; Paulina M. Strzelecka; Emmanouil I. Athanasiadis; Dominic Hall; Ana F. Robalo; Catherine M. Collins; Pierre Boudinot; Jean-Pierre Levraud; Ana Cvejic

doi:10.1126/sciimmunol.aau5265

Research ArticleINNATE LYMPHOID CELLS

Single-cell transcriptional analysis reveals ILC-like cells in zebrafish

Pedro P. Hernández ¹,²,*,†,
Paulina M. Strzelecka³,⁴,⁵,*,
Emmanouil I. Athanasiadis³,⁴,⁵,*,
Dominic Hall⁵,
Ana F. Robalo¹,²,
Catherine M. Collins⁶,
Pierre Boudinot⁷,
Jean-Pierre Levraud ¹,²,*,† and
Ana Cvejic ³,⁴,⁵,*,†

¹Macrophages et Développement de l'Immunité, Institut Pasteur, Paris, France.
²Centre National de la Recherche Scientifique, UMR3738, Paris, France.
³Department of Haematology, University of Cambridge, Cambridge, UK.
⁴Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.
⁵Wellcome Trust–Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.
⁶Marine Scotland Science, Marine Laboratory, Aberdeen, UK.
⁷Institut National de la Recherche Agronomique, Virologie et Immunologie Moléculaire, Jouy-en-Josas, France.

↵†Corresponding author. Email: as889{at}cam.ac.uk (A.C.); jean-pierre.levraud{at}pasteur.fr (J.-P.L.); pedro.hernandez-cerda{at}pasteur.fr (P.P.H.)

↵* These authors contributed equally to this work.

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Science Immunology 16 Nov 2018:
Vol. 3, Issue 29, eaau5265
DOI: 10.1126/sciimmunol.aau5265

Pedro P. Hernández

Macrophages et Développement de l'Immunité, Institut Pasteur, Paris, France.Centre National de la Recherche Scientifique, UMR3738, Paris, France.

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ORCID record for Pedro P. Hernández
For correspondence: as889@cam.ac.ukjean-pierre.levraud@pasteur.frpedro.hernandez-cerda@pasteur.fr

Paulina M. Strzelecka

Department of Haematology, University of Cambridge, Cambridge, UK.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK.Wellcome Trust–Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.

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Emmanouil I. Athanasiadis

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Dominic Hall

Wellcome Trust–Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.

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Ana F. Robalo

Macrophages et Développement de l'Immunité, Institut Pasteur, Paris, France.Centre National de la Recherche Scientifique, UMR3738, Paris, France.

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Catherine M. Collins

Marine Scotland Science, Marine Laboratory, Aberdeen, UK.

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Pierre Boudinot

Institut National de la Recherche Agronomique, Virologie et Immunologie Moléculaire, Jouy-en-Josas, France.

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Jean-Pierre Levraud

Macrophages et Développement de l'Immunité, Institut Pasteur, Paris, France.Centre National de la Recherche Scientifique, UMR3738, Paris, France.

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For correspondence: as889@cam.ac.ukjean-pierre.levraud@pasteur.frpedro.hernandez-cerda@pasteur.fr

Ana Cvejic

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For correspondence: as889@cam.ac.ukjean-pierre.levraud@pasteur.frpedro.hernandez-cerda@pasteur.fr

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Single-cell transcriptional analysis reveals ILC-like cells in zebrafish

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