Table 2 Characteristics of TrialNet cohort study participants.

Cases (n = 68)Controls (n = 62)
Sex (% males)n = 36 (53%)n = 32 (52%)
Age at T1D diagnosis
(years; mean ± SD)
11.61 (±3.76)N/A
Age at ACAb test
(years; mean ± SD)
10.67 (±3.82)10.92 (±3.65)
Time between ACAb
test and diagnosis
(days; mean ± SD)
344 (±120)N/A
Follow-up time (days;
mean ± SD)
1045 (±711)2646 (±1051)
HLA-DR3 positive/
DR4 negative
n = 20 (29%)n = 18 (29%)
HLA-DR3 negative/
DR4 positive
n = 22 (32%)n = 21 (34%)
HLA-DR3 positive/
DR4 positive
n = 12 (18%)n = 10 (16%)