A one-protein signaling pathway in the innate immune system

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Science Immunology  19 Aug 2016:
Vol. 1, Issue 2, pp. eaah6184
DOI: 10.1126/sciimmunol.aah6184

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Group A Streptococcus protease SpeB directly binds and activates IL-1β (LaRock et al., this issue).

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