Research ArticleINFECTIOUS DISEASE

The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness

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Science Immunology  09 Dec 2016:
Vol. 1, Issue 6, eaai8593
DOI: 10.1126/sciimmunol.aai8593

Article Information

vol. 1 no. 6

PubMed: 
Published By: 
History: 
  • Received August 23, 2016
  • Accepted November 14, 2016
  • .

Author Information

  1. Tuoqi Wu1,*,
  2. Yun Ji2,
  3. E. Ashley Moseman3,
  4. Haifeng C. Xu4,
  5. Monica Manglani3,
  6. Martha Kirby1,
  7. Stacie M. Anderson1,
  8. Robin Handon1,
  9. Elizabeth Kenyon3,
  10. Abdel Elkahloun1,
  11. Weiwei Wu1,
  12. Philipp A. Lang4,
  13. Luca Gattinoni2,
  14. Dorian B. McGavern3 and
  15. Pamela L. Schwartzberg1,*
  1. 1National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  2. 2National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  3. 3National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
  4. 4Department of Molecular Medicine II, Medical Faculty, Heinrich-Heine-University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.
  1. *Corresponding author. Email: pams{at}nhgri.nih.gov (P.L.S.); tuoqi.wu{at}nih.gov (T.W.)

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