April 2017
Vol 2, Issue 10

About The Cover

Cover image expansion

ONLINE COVER Promoting Tolerance. Depicted here is a type 1 regulatory T (TR1) cell (left) interacting with a dendritic cell (top right, dark purple) and an interleukin-27 (IL-27)–secreting macrophage (bottom right, light purple). Zhang et al. report that IL-27–driven commitment of T cells to the TR1 cell lineage limits graft-versus-host disease after bone marrow transplantation. [CREDIT: MADELEINE FLYNN, GRAPHIC SUPPORT OFFICER, QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE AND GARVIN GRULLÓN, AAAS]