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Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions

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Science Immunology  16 Jun 2017:
Vol. 2, Issue 12, eaai9297
DOI: 10.1126/sciimmunol.aai9297

Article Information

vol. 2 no. 12

PubMed: 
Published By: 
History: 
  • Received September 1, 2016
  • Accepted May 15, 2017
  • .

Author Information

  1. Khalid Bin Dhuban1,2,*,
  2. Eva d’Hennezel1,*,,
  3. Yasuhiro Nagai3,
  4. Yan Xiao3,
  5. Steven Shao1,2,
  6. Roman Istomine1,2,
  7. Fernando Alvarez1,2,
  8. Moshe Ben-Shoshan4,
  9. Hans Ochs5,
  10. Bruce Mazer4,6,
  11. Bin Li3,
  12. Chiyoko Sekine,
  13. Alan Berezov3,
  14. Wayne Hancock3,
  15. Troy R. Torgerson4,
  16. Mark I. Greene3 and
  17. Ciriaco A. Piccirillo1,2,6,8,
  1. 1Department of Microbiology and Immunology, McGill University and Research Institute of McGill University Health Centre, Montréal, Québec H3A 2B4, Canada.
  2. 2Program in Infectious Diseases and Immunology in Global Health, Centre for Translational Biology, Research Institute of McGill University Health Centre, Montréal, Québec H4A 3J1, Canada.
  3. 3Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104–6082, USA.
  4. 4Division of Pediatric Allergy and Clinical Immunology, Department of Pediatrics, McGill University Health Center, Montréal, Québec H3H 1P3, Canada.
  5. 5Department of Pediatrics, University of Washington School of Medicine, Seattle, WA 98101–1304, USA.
  6. 6FOCiS Centre of Excellence in Translational Immunology (CETI), Montréal, Québec H4A 3J1, Canada.
  7. 7Department of Clinical Research Medicine, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
  8. 8Division of Allergy and Clinical Immunology, Department of Medicine, McGill University and McGill University Health Centre, Montreal, Quebec, Canada.
  1. Corresponding author. Email: ciro.piccirillo{at}mcgill.ca
  1. * These authors contributed equally to this work.

  • Present address: Novartis Institutes for Biomedical Research Inc., Cambridge, MA 02139, USA.

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