Research ArticleAUTOIMMUNITY

Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα

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Science Immunology  09 Jun 2017:
Vol. 2, Issue 12, eaal3062
DOI: 10.1126/sciimmunol.aal3062

Article Information

vol. 2 no. 12

PubMed: 
Published By: 
History: 
  • Received October 29, 2016
  • Revision received March 12, 2017
  • Accepted May 9, 2017

Author Information

  1. Bo Sun1,2,*,
  2. Nishant Dwivedi1,2,*,
  3. Tyler J. Bechtel3,
  4. Janet L. Paulsen4,
  5. Aaron Muth4,
  6. Mandar Bawadekar5,
  7. Gang Li1,2,
  8. Paul R. Thompson4,
  9. Miriam A. Shelef6,
  10. Celia A. Schiffer4,
  11. Eranthie Weerapana3 and
  12. I-Cheng Ho1,2,
  1. 1Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA.
  2. 2Harvard Medical School, Boston, MA 02115, USA.
  3. 3Department of Chemistry, Boston College, Chestnut Hill, MA 02467, USA.
  4. 4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  5. 5Department of Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA.
  6. 6Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA.
  1. Corresponding author. Email: iho{at}partners.org
  1. * These authors contributed equally to this work.

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