Research ArticleINFECTIOUS DISEASE
Plasmodium products persist in the bone marrow and promote chronic bone loss
- Michelle S. J. Lee1,
- Kenta Maruyama2,
- Yukiko Fujita1,
- Aki Konishi1,
- Patrick M. Lelliott1,
- Sawako Itagaki3,
- Toshihiro Horii3,
- Jing-wen Lin4,5,
- Shahid M. Khan4,
- Etsushi Kuroda6,7,
- Shizuo Akira2,
- Ken J. Ishii6,7 and
- Cevayir Coban1,*
- 1Laboratory of Malaria Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
- 2Laboratory of Host Defense, IFReC, Osaka University, Suita, Osaka 565-0871, Japan.
- 3Department of Molecular Protozoology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
- 4Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Centre, 2333 ZA Leiden, Netherlands.
- 5Division of Pediatric Infectious Diseases, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University and Collaboration Innovation Centre, Chengdu 610041, China.
- 6Laboratory of Vaccine Science, IFReC, Osaka University, Suita, Osaka 565-0871, Japan.
- 7Laboratory of Adjuvant Innovation, National Institutes of Biomedical Innovation, Health and Nutrition, 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.
- ↵*Corresponding author. Email: ccoban{at}biken.osaka-u.ac.jp
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Science Immunology 02 Jun 2017:
Vol. 2, Issue 12, eaam8093
DOI: 10.1126/sciimmunol.aam8093
