Research ArticleINFECTIOUS DISEASE
Memory-phenotype CD4+ T cells spontaneously generated under steady-state conditions exert innate TH1-like effector function
- Takeshi Kawabe1,2,*,
- Dragana Jankovic2,
- Shuko Kawabe1,
- Yuefeng Huang1,
- Ping-Hsien Lee1,
- Hidehiro Yamane1,
- Jinfang Zhu3,
- Alan Sher2,*,
- Ronald N. Germain1,4,* and
- William E. Paul1,†
- 1Cytokine Biology Unit, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
- 2Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
- 3Molecular and Cellular Immunoregulation Unit, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
- 4Lymphocyte Biology Section, Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
- ↵*Corresponding author. Email: takeshi.kawabe{at}nih.gov (T.K.); asher{at}niaid.nih.gov (A.S.); rgermain{at}niaid.nih.gov (R.N.G.)
See allHide authors and affiliations
Science Immunology 16 Jun 2017:
Vol. 2, Issue 12, eaam9304
DOI: 10.1126/sciimmunol.aam9304
