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Tumor-derived exosomes modulate PD-L1 expression in monocytes

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Science Immunology  28 Jul 2017:
Vol. 2, Issue 13, eaah5509
DOI: 10.1126/sciimmunol.aah5509

Article Information

vol. 2 no. 13

PubMed: 
Published By: 
History: 
  • Received July 13, 2016
  • Revision received March 23, 2017
  • Accepted June 12, 2017
  • .

Author Information

  1. Franziska Haderk1,
  2. Ralph Schulz1,
  3. Murat Iskar1,
  4. Laura Llaó Cid1,
  5. Thomas Worst2,
  6. Karolin V. Willmund1,
  7. Angela Schulz1,3,
  8. Uwe Warnken3,
  9. Jana Seiler4,
  10. Axel Benner5,
  11. Michelle Nessling6,
  12. Thorsten Zenz7,
  13. Maria Göbel8,
  14. Jan Dürig8,
  15. Sven Diederichs4,9,10,
  16. Jérôme Paggetti11,
  17. Etienne Moussay11,
  18. Stephan Stilgenbauer12,
  19. Marc Zapatka1,
  20. Peter Lichter1 and
  21. Martina Seiffert1,*
  1. 1Department of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  2. 2Division of Signaling and Functional Genomics, DKFZ, Heidelberg, Germany.
  3. 3Genomics and Proteomics Core Facility, DKFZ, Heidelberg, Germany.
  4. 4Division of RNA Biology and Cancer (B150), DKFZ, Heidelberg, Germany.
  5. 5Division of Biostatistics, DKFZ, Heidelberg, Germany.
  6. 6Central Unit Electron Microscopy, DKFZ, Heidelberg, Germany.
  7. 7Department of Molecular Therapy in Hematology and Oncology and Department of Translational Oncology, National Center for Tumor Diseases (NCT); DKFZ; and Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany.
  8. 8Department of Hematology, Essen University Hospital, Essen, Germany.
  9. 9Division of Cancer Research, Department of Thoracic Surgery, Medical Center–Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  10. 10German Cancer Consortium (DKTK), Freiburg, Germany.
  11. 11Laboratory of Experimental Cancer Research, Luxembourg Institute of Health, Luxembourg City, Luxembourg.
  12. 12Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany.
  1. *Corresponding author. Email: m.seiffert{at}dkfz.de

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