Research ArticleINFECTIOUS DISEASE
Recovery from the Middle East respiratory syndrome is associated with antibody and T cell responses
- Jingxian Zhao1,2,*,
- Abeer N. Alshukairi3,*,†,
- Salim A. Baharoon4,
- Waleed A. Ahmed3,
- Ahmad A. Bokhari3,
- Atef M. Nehdi5,
- Laila A. Layqah5,
- Mohammed G. Alghamdi6,
- Manal M. Al Gethamy7,
- Ashraf M. Dada3,
- Imran Khalid3,
- Mohamad Boujelal5,
- Sameera M. Al Johani4,
- Leatrice Vogel8,
- Kanta Subbarao8,‡,
- Ashutosh Mangalam9,
- Chaorong Wu10,
- Patrick Ten Eyck10,
- Stanley Perlman2,† and
- Jincun Zhao1,11,†
- 1State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510182, China.
- 2Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242, USA.
- 3King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia.
- 4King Saud bin Abdulaziz for Health Sciences University, Riyadh, Kingdom of Saudi Arabia.
- 5King Abdullah International Medical Research Center, Riyadh, Kingdom of Saudi Arabia.
- 6King Fahd General Hospital, Jeddah, Kingdom of Saudi Arabia.
- 7Al Nour Specialist Hospital, Makkah, Kingdom of Saudi Arabia.
- 8Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
- 9Department of Pathology, University of Iowa, Iowa City, IA 52242, USA.
- 10Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA 52242, USA.
- 11Guangzhou Eighth People’s Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510000, China.
- ↵†Corresponding author. Email: stanley-perlman{at}uiowa.edu (S.P.); zhaojincun{at}gird.cn (J.Z.); aalshukairi{at}kfshrc.edu.sa (A.N.A.)
↵* These authors contributed equally to this work.
↵‡ Present address: World Health Organization Collaborating Centre for Reference and Research on Influenza, Peter Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Melbourne, Victoria, Australia.
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Science Immunology 04 Aug 2017:
Vol. 2, Issue 14, eaan5393
DOI: 10.1126/sciimmunol.aan5393
Vol. 2, Issue 14, eaan5393
DOI: 10.1126/sciimmunol.aan5393
Jingxian Zhao
State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510182, China.Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242, USA.
Abeer N. Alshukairi
King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia.
Salim A. Baharoon
King Saud bin Abdulaziz for Health Sciences University, Riyadh, Kingdom of Saudi Arabia.
Waleed A. Ahmed
King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia.
Ahmad A. Bokhari
King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia.
Atef M. Nehdi
King Abdullah International Medical Research Center, Riyadh, Kingdom of Saudi Arabia.
Laila A. Layqah
King Abdullah International Medical Research Center, Riyadh, Kingdom of Saudi Arabia.
Mohammed G. Alghamdi
King Fahd General Hospital, Jeddah, Kingdom of Saudi Arabia.
Manal M. Al Gethamy
Al Nour Specialist Hospital, Makkah, Kingdom of Saudi Arabia.
Ashraf M. Dada
King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia.
Imran Khalid
King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia.
Mohamad Boujelal
King Abdullah International Medical Research Center, Riyadh, Kingdom of Saudi Arabia.
Sameera M. Al Johani
King Saud bin Abdulaziz for Health Sciences University, Riyadh, Kingdom of Saudi Arabia.
Leatrice Vogel
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Kanta Subbarao
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Ashutosh Mangalam
Department of Pathology, University of Iowa, Iowa City, IA 52242, USA.
Chaorong Wu
Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA 52242, USA.
Patrick Ten Eyck
Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA 52242, USA.
Stanley Perlman
Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242, USA.
Jincun Zhao
State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510182, China.Guangzhou Eighth People’s Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510000, China.
