October 2017
Vol 2, Issue 16

About The Cover

Cover image expansion

ONLINE COVER Lining Up to Defend. An image of a spleen from a mouse infected with Listeria monocytogenes was stained for CD169+ marginal zone macrophages (red), L. monocytogenes (green), and B cells (blue). Perez et al. show that strategically positioned marginal zone macrophages drive immune responses to L. monocytogenes by controlling pathogen localization in the spleen. [CREDIT: PEREZ ET AL./SCIENCE IMMUNOLOGY]