February 2017
Vol 2, Issue 8

About The Cover

Cover image expansion

ONLINE COVER "Iron"ic Immunity. Pathogens rely entirely on the host as their source of iron, an essential nutrient. Using Citrobacter rodentium as a model of systemic infection, Sakamoto et al. uncover a role for the cytokine interleukin-22 in inducing iron sequestration from pathogens, restricting bacterial growth. See the related Focus by Datta. [CREDIT: GIPHOTOSTOCK/SCIENCE SOURCE]