Research ArticleINFECTIOUS DISEASE

Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis

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Science Immunology  24 Mar 2017:
Vol. 2, Issue 9, eaaj1789
DOI: 10.1126/sciimmunol.aaj1789

Article Information

vol. 2 no. 9

PubMed: 
Published By: 
History: 
  • Received September 8, 2016
  • Revision received December 27, 2016
  • Accepted February 12, 2017

Author Information

  1. Catherine Y. Cheng1,
  2. Nuria M. Gutierrez2,
  3. Mardiana B. Marzuki1,
  4. Xiaohua Lu1,
  5. Taylor W. Foreman3,
  6. Bhairav Paleja1,
  7. Bernett Lee1,
  8. Akhila Balachander1,
  9. Jinmiao Chen1,
  10. Liana Tsenova4,5,
  11. Natalia Kurepina4,
  12. Karen W. W. Teng1,
  13. Kim West2,
  14. Smriti Mehra6,
  15. Francesca Zolezzi1,*,
  16. Michael Poidinger1,
  17. Barry Kreiswirth4,
  18. Deepak Kaushal3,
  19. Hardy Kornfeld2,
  20. Evan W. Newell1 and
  21. Amit Singhal1,7,
  1. 1Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore 138648, Singapore.
  2. 2Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  3. 3Tulane National Primate Research Center, Covington, LA 70433, USA.
  4. 4Public Health Research Institute of Rutgers Biomedical and Health Sciences, Rutgers University, Newark, NJ 07103, USA.
  5. 5New York City College of Technology, Brooklyn, NY 11201, USA.
  6. 6Louisiana State University School of Veterinary Medicine, Baton Rouge, LA 70803, USA.
  7. 7Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
  1. Corresponding author. Email: amit_singhal{at}immunol.a-star.edu.sg
  • * Present address: Galderma R&D, 06902 Sophia Antipolis Cedex, France.

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