Research ArticleCANCER IMMUNOLOGY

Tumor immune evasion arises through loss of TNF sensitivity

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Science Immunology  18 May 2018:
Vol. 3, Issue 23, eaar3451
DOI: 10.1126/sciimmunol.aar3451

Article Information

vol. 3 no. 23

PubMed: 
Published By: 
History: 
  • Received October 27, 2017
  • Accepted March 29, 2018

Author Information

  1. Conor J. Kearney1,2,*,
  2. Stephin J. Vervoort2,3,*,
  3. Simon J. Hogg2,3,
  4. Kelly M. Ramsbottom1,
  5. Andrew J. Freeman1,
  6. Najoua Lalaoui4,
  7. Lizzy Pijpers1,
  8. Jessica Michie1,
  9. Kristin K. Brown2,5,6,
  10. Deborah A. Knight2,
  11. Vivien Sutton7,
  12. Paul A. Beavis2,8,
  13. Ilia Voskoboinik2,9,
  14. Phil K. Darcy2,8,
  15. John Silke4,
  16. Joseph A. Trapani2,7,
  17. Ricky W. Johnstone2,3,, and
  18. Jane Oliaro1,2,,
  1. 1Immune Defence Laboratory, Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
  2. 2Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria 3052, Australia.
  3. 3Gene Regulation Laboratory, Translational Haematology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
  4. 4Cell Signalling and Cell Death Division, Walter and Eliza Hall Institute for Medical Research, Parkville, Victoria 3050, Australia.
  5. 5Cancer Therapeutics and Cancer Metabolism Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
  6. 6Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3052, Australia.
  7. 7Cancer Cell Death Laboratory, Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3000, Australia.
  8. 8Immunotherapy Laboratory, Cancer Immunology Program, Peter MacCallum Cancer Center, East Melbourne, Victoria 3000, Australia.
  9. 9Killer Cell Biology Laboratory, Cancer Immunology Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3000, Australia.
  1. Corresponding author. Email: ricky.johnstone{at}petermac.org (R.W.J.); jane.oliaro{at}petermac.org (J.O.)
  1. * These authors contributed equally to this work.

  2. These authors contributed equally to this work.

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