July 2018
Vol 3, Issue 25

About The Cover

Cover image expansion

ONLINE COVER Binary Decision. Featured on the cover is a photograph of two of the moai statues located on Rapa Nui (Easter Island), a Polynesian island where a Streptomyces bacterial strain was isolated that yielded the macrolide drug rapamycin. Yang et al. report that commitment of T cell precursors to the αβ T cell lineage is compromised in mice with perturbed metabolic signaling caused by absence of the RAPTOR protein, an essential component of the mechanistic target of rapamycin complex 1 (mTORC1). The number two is the organizing theme of this second anniversary issue. [CREDIT:]