Research ArticleMICROBIAL IMMUNITY

MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

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Science Immunology  13 Jul 2018:
Vol. 3, Issue 25, eaao2556
DOI: 10.1126/sciimmunol.aao2556

Article Information

vol. 3 no. 25

PubMed: 
Published By: 
History: 
  • Received June 30, 2017
  • Revision received February 5, 2018
  • Accepted June 4, 2018
  • .

Author Information

  1. Melanie J. Harriff1,2,*,
  2. Curtis McMurtrey3,*,
  3. Cara A. Froyd4,*,
  4. Haihong Jin5,*,
  5. Meghan Cansler6,
  6. Megan Null6,
  7. Aneta Worley1,
  8. Erin W. Meermeier2,
  9. Gwendolyn Swarbrick6,
  10. Aaron Nilsen1,5,7,
  11. Deborah A. Lewinsohn6,
  12. William Hildebrand3,,
  13. Erin J. Adams4, and
  14. David M. Lewinsohn1,2,,
  1. 1VA Portland Health Care System, Research and Development, 3710 Southwest U.S. Veterans Hospital Road, Portland, OR 97239, USA.
  2. 2Department of Pulmonary and Critical Care Medicine, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.
  3. 3Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
  4. 4Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.
  5. 5Oregon Health & Science University Medicinal Chemistry Core, Portland, OR 97239, USA.
  6. 6Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA.
  7. 7Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA.
  1. Corresponding author. Email: lewinsod{at}ohsu.edu
  1. * These authors contributed equally to this work as co-first authors.

  2. These authors contributed equally to this work as co-senior authors.

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