Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria

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Science Immunology  31 Aug 2018:
Vol. 3, Issue 26, eaat7668
DOI: 10.1126/sciimmunol.aat7668

Article Information

vol. 3 no. 26

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  • Received April 2, 2018
  • Accepted July 3, 2018
  • .

Author Information

  1. Samuel J. Balin1,2,
  2. Matteo Pellegrini3,
  3. Eynav Klechevsky4,
  4. Sohui T. Won2,
  5. David I. Weiss5,
  6. Aaron W. Choi2,
  7. Joshua Hakimian2,
  8. Jing Lu3,
  9. Maria Teresa Ochoa6,
  10. Barry R. Bloom7,
  11. Lewis L. Lanier8,
  12. Steffen Stenger9 and
  13. Robert L. Modlin1,2,*
  1. 1Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
  2. 2Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  3. 3Molecular Cell and Developmental Biology at UCLA, Los Angeles, CA 90095, USA.
  4. 4Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63108, USA.
  5. 5Molecular Biology Interdepartmental Graduate Program, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  6. 6Department of Dermatology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA.
  7. 7Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  8. 8Department of Microbiology and Immunology and the Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA 94143, USA.
  9. 9Institute for Medical Microbiology and Hygiene, University Hospital Ulm, Ulm, Germany.
  1. *Corresponding author. Email: rmodlin{at}


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