Research ArticleINFECTIOUS DISEASES
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria
- Samuel J. Balin1,2,
- Matteo Pellegrini3,
- Eynav Klechevsky4,
- Sohui T. Won2,
- David I. Weiss5,
- Aaron W. Choi2,
- Joshua Hakimian2,
- Jing Lu3,
- Maria Teresa Ochoa6,
- Barry R. Bloom7,
- Lewis L. Lanier8,
- Steffen Stenger9 and
- Robert L. Modlin1,2,*
- 1Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.
- 2Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
- 3Molecular Cell and Developmental Biology at UCLA, Los Angeles, CA 90095, USA.
- 4Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63108, USA.
- 5Molecular Biology Interdepartmental Graduate Program, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
- 6Department of Dermatology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA.
- 7Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
- 8Department of Microbiology and Immunology and the Parker Institute for Cancer Immunotherapy, University of California, San Francisco, San Francisco, CA 94143, USA.
- 9Institute for Medical Microbiology and Hygiene, University Hospital Ulm, Ulm, Germany.
- ↵*Corresponding author. Email: rmodlin{at}mednet.ucla.edu
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Science Immunology 31 Aug 2018:
Vol. 3, Issue 26, eaat7668
DOI: 10.1126/sciimmunol.aat7668
