Research ArticleANTIGEN PRESENTATION

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

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Science Immunology  12 Oct 2018:
Vol. 3, Issue 28, eaar3947
DOI: 10.1126/sciimmunol.aar3947

Article Information

vol. 3 no. 28

PubMed: 
Published By: 
History: 
  • Received November 2, 2017
  • Revision received May 29, 2018
  • Accepted August 31, 2018
  • .

Author Information

  1. Pouya Faridi1,
  2. Chen Li1,2,
  3. Sri H. Ramarathinam1,
  4. Julian P. Vivian1,3,
  5. Patricia T. Illing1,
  6. Nicole A. Mifsud1,
  7. Rochelle Ayala1,
  8. Jiangning Song1,4,
  9. Linden J. Gearing5,
  10. Paul J. Hertzog5,
  11. Nicola Ternette6,
  12. Jamie Rossjohn1,3,7,
  13. Nathan P. Croft1,* and
  14. Anthony W. Purcell1,*
  1. 1Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  2. 2Department of Biology, Institute of Molecular Systems Biology,ETH Zurich, Zurich 8093, Switzerland.
  3. 3Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia.
  4. 4Monash Centre for Data Science, Faculty of Information Technology, Monash University, Melbourne, Victoria 3800, Australia.
  5. 5Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research and Department of Molecular and Translational Science, School of Clinical Science, Monash University, Clayton, Victoria 3168, Australia.
  6. 6Jenner Institute, University of Oxford, Oxford OX3 7FZ, UK.
  7. 7Institute of Infection and Immunity, Cardiff University School of Medicine,Heath Park, Cardiff CF14 4XN, UK.
  1. *Corresponding author. Email: anthony.purcell{at}monash.edu (A.W.P.); nathan.croft{at}monash.edu (N.P.C.)

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