Research ArticleCANCER IMMUNOLOGY

The immune system profoundly restricts intratumor genetic heterogeneity

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Science Immunology  23 Nov 2018:
Vol. 3, Issue 29, eaat1435
DOI: 10.1126/sciimmunol.aat1435

Article Information

vol. 3 no. 29

PubMed: 
Published By: 
History: 
  • Received January 29, 2018
  • Revision received August 3, 2018
  • Accepted October 18, 2018
  • .

Author Information

  1. Idan Milo1,2,
  2. Marie Bedora-Faure3,
  3. Zacarias Garcia1,2,
  4. Ronan Thibaut1,2,4,
  5. Leïla Périé5,6,
  6. Guy Shakhar7,
  7. Ludovic Deriano3 and
  8. Philippe Bousso1,2,*
  1. 1Dynamics of Immune Responses Unit, Equipe Labellisée Ligue Contre le Cancer, Institut Pasteur, 75015 Paris, France.
  2. 2INSERM U1223, 75015 Paris, France.
  3. 3Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France.
  4. 4University Paris Diderot, Sorbonne Paris Cité, Cellule Pasteur, rue du Dr Roux, 75015 Paris, France.
  5. 5Institut Curie, PSL Research University, CNRS UMR168, 11 rue Pierre et Marie Curie, 75005 Paris, France.
  6. 6Sorbonne Universités, UPMC University Paris 06, 4 place Jussieu, 75005 Paris, France.
  7. 7Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
  1. *Corresponding author. Email: philippe.bousso{at}pasteur.fr

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