Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation

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  Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation

  By Sarah Mundt, Dunja Mrdjen, Sebastian G. Utz, Melanie Greter, Bettina Schreiner, Burkhard Becher

  Science Immunology25 Jan 2019

  In vivo reactivation of myelin-reactive T cells requires conventional DCs but not other brain-resident antigen-presenting cells.

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  Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation

  By Sarah Mundt, Dunja Mrdjen, Sebastian G. Utz, Melanie Greter, Bettina Schreiner, Burkhard Becher

  Science Immunology25 Jan 2019

  In vivo reactivation of myelin-reactive T cells requires conventional DCs but not other brain-resident antigen-presenting cells.

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