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Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection

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Science Immunology  08 Feb 2019:
Vol. 4, Issue 32, eaau6905
DOI: 10.1126/sciimmunol.aau6905

Article Information

vol. 4 no. 32

Published By: 
  • Received July 6, 2018
  • Accepted January 2, 2019

Author Information

  1. Yang Cheng1,
  2. Yuan O. Zhu2,
  3. Etienne Becht1,
  4. Pauline Aw2,
  5. Jinmiao Chen1,
  6. Michael Poidinger1,
  7. Paola Flórez de Sessions2,
  8. Martin Lloyd Hibberd2,3,
  9. Antonio Bertoletti1,4,
  10. Seng Gee Lim5 and
  11. Evan W. Newell1,6,*
  1. 1Singapore Immunology Network, Agency for Science, Technology and Research, Singapore.
  2. 2Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.
  3. 3Emerging Infectious Disease, Department of Pathogen Molecular Biology, London School of Hygiene & Tropical Medicine, London, UK.
  4. 4Emerging Infectious Disease Program, Duke-NUS Medical School, Singapore.
  5. 5Division of Gastroenterology & Hepatology, National University Health System, Singapore.
  6. 6Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  1. *Corresponding author. Email: enewell{at}


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Mar 201985110163
Apr 20193876940