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Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes

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Science Immunology  22 Feb 2019:
Vol. 4, Issue 32, eaav5062
DOI: 10.1126/sciimmunol.aav5062

Article Information

vol. 4 no. 32

PubMed: 
Published By: 
History: 
  • Received September 24, 2018
  • Accepted January 11, 2019

Author Information

  1. Julie M. Fox1,
  2. Vicky Roy2,
  3. Bronwyn M. Gunn2,
  4. Ling Huang3,
  5. Melissa A. Edeling4,
  6. Matthias Mack5,
  7. Daved H. Fremont4,6,
  8. Benjamin J. Doranz7,
  9. Syd Johnson3,
  10. Galit Alter2 and
  11. Michael S. Diamond1,4,6,*
  1. 1Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.
  2. 2Ragon Institute of MGH, MIT, and Harvard University, Cambridge, MA 02139, USA.
  3. 3MacroGenics, Rockville, MD 20850, USA.
  4. 4Department of Pathology & Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  5. 5Regensburg University Medical Center, Regensburg 93042, Germany.
  6. 6Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  7. 7Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  1. *Corresponding author. Email: mdiamond{at}wustl.edu

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Mar 2019391791214
Apr 20192608543
May 20191854824
Jun 20192193115
Jul 2019592010