Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors
- View ORCID ProfileMar Cabeza-Cabrerizo1,*,†,
- Janneke van Blijswijk1,*,†,
- Stephan Wienert2,‡,
- View ORCID ProfileDaniel Heim2,
- View ORCID ProfileRobert P. Jenkins3,
- View ORCID ProfileProbir Chakravarty4,
- Neil Rogers1,
- View ORCID ProfileBruno Frederico1,
- View ORCID ProfileSophie Acton1,§,
- Evelyne Beerling5,||,
- Jacco van Rheenen5,||,
- View ORCID ProfileHans Clevers5,
- View ORCID ProfileBarbara U. Schraml1,¶,
- Marc Bajénoff6,
- View ORCID ProfileMichael Gerner7,#,
- Ronald N. Germain7,
- View ORCID ProfileErik Sahai3,
- Frederick Klauschen2,† and
- View ORCID ProfileCaetano Reis e Sousa1,†
- 1Immunobiology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
- 2Institute of Pathology, Charité University Medicine Berlin, Charitéplatz 1, D-10117 Berlin, Germany.
- 3Tumour Cell Biology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
- 4Bioinformatics, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
- 5Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, Netherlands.
- 6Aix-Marseille University Centre, National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Immunologie de Marseille-Luminy (CIML), Marseille, France.
- 7Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
- ↵†Corresponding author. Email: caetano{at}crick.ac.uk (C.R.e.S); mar.cabeza-cabrerizo{at}crick.ac.uk (M.C.-C.); jannekevanblijswijk{at}gmail.com (J.v.B.); frederick.klauschen{at}charite.de (F.K.)
↵* These authors contributed equally to this work.
↵‡ Present address: dlw Laborsoftware UG, Kastanienallee 36, 15907 Lübben, Germany.
↵§ Present address: MRC Laboratory for Molecular Cell Biology, University College London, WC1E 6BT, UK.
↵|| Present address: Netherlands Cancer Institute, Division of Molecular Pathology, Plesmanlaan 121, 1066 CX Amsterdam, Netherlands.
↵¶ Present address: Walter-Brendel-Centre for Experimental Medicine, University Hospital, LMU Munich, Grosshaderner Strasse 9, 82152 Planegg-Martinsried and Biomedical Center, LMU Munich, Grosshaderner Strasse 9, 82152 Planegg-Martinsried, Germany.
↵# Present address: Department of Immunology, University of Washington School of Medicine, Seattle, WA 98109, USA.
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Vol. 4, Issue 33, eaaw1941
DOI: 10.1126/sciimmunol.aaw1941