Research ArticleVACCINES

Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine

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Science Immunology  19 Apr 2019:
Vol. 4, Issue 34, eaau2710
DOI: 10.1126/sciimmunol.aau2710

Article Information

vol. 4 no. 34

PubMed: 
Published By: 
History: 
  • Received May 24, 2018
  • Accepted March 18, 2019
  • .

Author Information

  1. Kenta Matsuda1,*,
  2. Jinghe Huang1,*,
  3. Tongqing Zhou2,
  4. Zizhang Sheng3,
  5. Byong H. Kang1,
  6. Elise Ishida1,
  7. Trevor Griesman1,
  8. Sarah Stuccio1,
  9. Lyuba Bolkhovitinov1,
  10. Teddy J. Wohlbold4,
  11. Veronika Chromikova4,
  12. Alberto Cagigi2,
  13. Kwanyee Leung2,
  14. Sarah Andrews2,
  15. Crystal S. F. Cheung2,
  16. Alyssa A. Pullano1,
  17. Jason Plyler2,
  18. Cinque Soto2,
  19. Baoshan Zhang2,
  20. Yongping Yang2,
  21. M. Gordon Joyce2,
  22. Yaroslav Tsybovsky5,
  23. Adam Wheatley2,
  24. Sandeep R. Narpala2,
  25. Yicheng Guo3,
  26. Sam Darko2,
  27. Robert T. Bailer2,
  28. April Poole1,
  29. C. Jason Liang6,
  30. Jon Smith7,
  31. Jeff Alexander7,
  32. Marc Gurwith7,
  33. Stephen A. Migueles1,
  34. Richard A. Koup2,
  35. Hana Golding8,
  36. Surender Khurana8,
  37. Adrian B. McDermott2,
  38. Lawrence Shapiro3,
  39. Florian Krammer4,
  40. Peter D. Kwong2 and
  41. Mark Connors1,
  1. 1HIV-Specific Immunity Section of the Laboratory of Immunoregulation, National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  2. 2Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  3. 3Department of Biochemistry and Molecular Biophysics, Zukerman Institute of Mind Brain Behavior, Columbia University, New York, NY 10032, USA.
  4. 4Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  5. 5Electron Microscopy Laboratory, Cancer Research Technology Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21701, USA.
  6. 6Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  7. 7Emergent Biosolutions Inc., Gaithersburg, MD 20879, USA.
  8. 8Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Admnistration, Silver Spring, MD 20993, USA.
  1. Corresponding author. Email: mconnors{at}nih.gov
  • * These authors contributed equally to this work.

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