Research ArticleEMERGING INFECTIONS

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

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Science Immunology  17 May 2019:
Vol. 4, Issue 35, eaaw6647
DOI: 10.1126/sciimmunol.aaw6647

Article Information

vol. 4 no. 35

PubMed: 
Published By: 
History: 
  • Received January 14, 2019
  • Accepted March 28, 2019
  • .

Author Information

  1. Nurgun Kose1,
  2. Julie M. Fox2,
  3. Gopal Sapparapu1,3,
  4. Robin Bombardi1,
  5. Rashika N. Tennekoon4,
  6. A. Dharshan de Silva4,5,
  7. Sayda M. Elbashir6,
  8. Matthew A. Theisen6,
  9. Elisabeth Humphris-Narayanan6,
  10. Giuseppe Ciaramella6,
  11. Sunny Himansu6,
  12. Michael S. Diamond2,7 and
  13. James E. Crowe Jr.1,3,8,*
  1. 1Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN, USA.
  2. 2Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  3. 3Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
  4. 4Genetech Research Institute, Colombo, Sri Lanka.
  5. 5Department of Paraclinical Sciences, Faculty of Medicine, Kotelawala Defence University, Sri Lanka.
  6. 6Moderna Therapeutics, Cambridge, MA, USA.
  7. 7Department of Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.
  8. 8Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
  1. *Corresponding author. Email: james.crowe{at}vanderbilt.edu

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Article usage: May 2019 to October 2019

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Aug 20193748752
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Oct 20192826749