FocusINFLAMMATION

Igniting the flame in arthritis: C5aR2 controls endothelial transcytosis of C5a

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Science Immunology  10 May 2019:
Vol. 4, Issue 35, eaax0352
DOI: 10.1126/sciimmunol.aax0352

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Abstract

C5aR2 transports C5a generated in the arthritic joint to the blood vessel endothelium as the first step in C5aR1-driven neutrophil arrest and crawling.

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