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IL-23–producing IL-10Rα–deficient gut macrophages elicit an IL-22–driven proinflammatory epithelial cell response

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Science Immunology  14 Jun 2019:
Vol. 4, Issue 36, eaau6571
DOI: 10.1126/sciimmunol.aau6571

Article Information

vol. 4 no. 36

PubMed: 
Published By: 
History: 
  • Received July 3, 2018
  • Revision received February 14, 2019
  • Accepted April 19, 2019
  • .

Author Information

  1. Biana Bernshtein1,
  2. Caterina Curato1,
  3. Marianna Ioannou2,
  4. Christoph A. Thaiss1,
  5. Mor Gross-Vered1,
  6. Masha Kolesnikov1,
  7. Qian Wang2,
  8. Eyal David1,
  9. Louise Chappell-Maor1,
  10. Alon Harmelin3,
  11. Eran Elinav1,
  12. Paresh Thakker4,
  13. Venizelos Papayannopoulos2 and
  14. Steffen Jung1,*
  1. 1Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.
  2. 2Francis Crick Institute, London NW1 1AT, UK.
  3. 3Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 76100, Israel.
  4. 4Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River, Tarrytown, NY 10591, USA.
  1. *Corresponding author. Email: s.jung{at}weizmann.ac.il

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