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Binding is not enough; autoantibodies do more to garner complements

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Science Immunology  05 Jul 2019:
Vol. 4, Issue 37, eaax9510
DOI: 10.1126/sciimmunol.aax9510

Abstract

Pathogenic autoantibodies in neuromyelitis optica require antigen array assembly and a specific epitope to initiate robust complement activation.

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