Research ArticleNK CELLS

Gab3 is required for IL-2– and IL-15–induced NK cell expansion and limits trophoblast invasion during pregnancy

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Science Immunology  02 Aug 2019:
Vol. 4, Issue 38, eaav3866
DOI: 10.1126/sciimmunol.aav3866

Article Information

vol. 4 no. 38

PubMed: 
Published By: 
History: 
  • Received September 12, 2018
  • Accepted July 3, 2019
  • .

Author Information

  1. Anna Sliz1,2,3,
  2. Kathryn C. S. Locker1,2,3,
  3. Kristin Lampe1,2,
  4. Alzbeta Godarova4,
  5. David R. Plas5,
  6. Edith M. Janssen6,
  7. Helen Jones7,8,
  8. Andrew B. Herr1,2,3 and
  9. Kasper Hoebe6,*
  1. 1Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45220, USA.
  2. 2Division of Immunobiology, Cincinnati Children’s Hospital Research Foundation, Cincinnati, OH 45229, USA.
  3. 3Immunology Graduate Program, Cincinnati Children’s Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45220, USA.
  4. 4Biomedical Informatics Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH 45220, USA.
  5. 5Vontz Center for Molecular Studies, University of Cincinnati, Cincinnati, OH 45267, USA.
  6. 6Janssen R&D, Spring House, PA 19002, USA.
  7. 7Division of General Pediatric and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.
  8. 8Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH 45220, USA.
  1. *Corresponding author. Email: khoebe{at}its.jnj.com

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