Research ArticleCANCER IMMUNOLOGY
Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity
- View ORCID ProfileZhida Liu1,*,
- View ORCID ProfileChuanhui Han1,*,
- View ORCID ProfileChunbo Dong1,
- View ORCID ProfileAijun Shen1,
- View ORCID ProfileEric Hsu1,2,
- View ORCID ProfileZhenhua Ren1,
- View ORCID ProfileChangzheng Lu1,
- View ORCID ProfileLongchao Liu1,
- View ORCID ProfileAnli Zhang1,
- View ORCID ProfileCasey Timmerman1,2,
- Yang Pu1,
- View ORCID ProfileYang Wang1,
- View ORCID ProfileMingyi Chen1,
- Jian Qiao1 and
- View ORCID ProfileYang-Xin Fu1,2,†
- 1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
- 2Department of Immunology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
- ↵†Corresponding author. Email: Yang-Xin.Fu{at}UTSouthwestern.edu
↵* These authors contributed equally to this work.
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Science Immunology 09 Aug 2019:
Vol. 4, Issue 38, eaav6473
DOI: 10.1126/sciimmunol.aav6473
Vol. 4, Issue 38, eaav6473
DOI: 10.1126/sciimmunol.aav6473
Zhida Liu
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Chuanhui Han
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Chunbo Dong
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Aijun Shen
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Eric Hsu
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
2Department of Immunology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Zhenhua Ren
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Changzheng Lu
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Longchao Liu
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Anli Zhang
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Casey Timmerman
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
2Department of Immunology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Yang Pu
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Yang Wang
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Mingyi Chen
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Jian Qiao
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
Yang-Xin Fu
1Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75235, USA.
2Department of Immunology, UT Southwestern Medical Center, Dallas, TX 75235, USA.