Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-T_FH cells

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  Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-T_FH cells

  By Amber Papillion, Michael D. Powell, Danielle A. Chisolm, Holly Bachus, Michael J. Fuller, Amy S. Weinmann, Alejandro Villarino, John J. O’Shea, Beatriz León, Kenneth J. Oestreich, André Ballesteros-Tato

  Science Immunology13 Sep 2019

  IL-6–mediated inhibition of CD122 allows T_FH cells to receive TCR signaling without initiating an inhibitory TCR/IL-2 loop (see the related Focus by Zhou and Yu)..

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  Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-T_FH cells

  By Amber Papillion, Michael D. Powell, Danielle A. Chisolm, Holly Bachus, Michael J. Fuller, Amy S. Weinmann, Alejandro Villarino, John J. O’Shea, Beatriz León, Kenneth J. Oestreich, André Ballesteros-Tato

  Science Immunology13 Sep 2019

  IL-6–mediated inhibition of CD122 allows T_FH cells to receive TCR signaling without initiating an inhibitory TCR/IL-2 loop (see the related Focus by Zhou and Yu)..

  • Supplementary Materials

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