Research ArticleB CELLS
Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-TFH cells
- Amber Papillion1,
- Michael D. Powell2,3,
- Danielle A. Chisolm4,
- Holly Bachus1,
- Michael J. Fuller1,
- Amy S. Weinmann4,
- Alejandro Villarino5,
- John J. O’Shea5,
- Beatriz León4,
- Kenneth J. Oestreich2,6,7 and
- André Ballesteros-Tato1,*
- 1Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
- 2Virginia Tech Carilion Research Institute, Roanoke, VA, USA.
- 3Translational Biology, Medicine, and Health Graduate Program, Virginia Tech Carilion Research Institute, Roanoke, VA, USA.
- 4Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.
- 5Molecular Immunology and Inflammation Branch, NIAMS, NIH, Bethesda, MD, USA.
- 6Virginia Tech Carilion School of Medicine, Roanoke, VA, USA.
- 7Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.
- ↵*Corresponding author. Email: andreballesterostato{at}uabmc.edu
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Science Immunology 13 Sep 2019:
Vol. 4, Issue 39, eaaw7636
DOI: 10.1126/sciimmunol.aaw7636
