Research ArticleT CELL DIFFERENTIATION
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells
- View ORCID ProfileMelissa S. F. Ng1,2,
- View ORCID ProfileTheodore L. Roth1,3,4,
- Ventura F. Mendoza5,
- View ORCID ProfileAlexander Marson3,4,6,7,8,9,10 and
- View ORCID ProfileTrevor D. Burt5,11,*,†
- 1Biomedical Sciences Graduate Program, University of California, San Francisco (UCSF), San Francisco, CA 94143, USA.
- 2Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Singapore 138648, Singapore.
- 3Department of Microbiology and Immunology, UCSF, San Francisco, CA 94143, USA.
- 4Diabetes Center, UCSF, San Francisco, CA 94143, USA.
- 5Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, CA 94143, USA.
- 6Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.
- 7Department of Medicine, UCSF, San Francisco, CA 94143, USA.
- 8Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
- 9UCSF Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA 94158, USA.
- 10Parker Institute for Cancer Immunotherapy, San Francisco, CA 94129, USA.
- 11Department of Pediatrics, Division of Neonatology, UCSF, San Francisco, CA 94110, USA.
- ↵*Corresponding author. Email: trevor.burt{at}duke.edu
↵† Present address: Department of Pediatrics, Division of Neonatology, Duke University School of Medicine, Durham, NC 27710, USA.
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Science Immunology 22 Nov 2019:
Vol. 4, Issue 41, eaav5947
DOI: 10.1126/sciimmunol.aav5947
Vol. 4, Issue 41, eaav5947
DOI: 10.1126/sciimmunol.aav5947
Melissa S. F. Ng
1Biomedical Sciences Graduate Program, University of California, San Francisco (UCSF), San Francisco, CA 94143, USA.
2Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Singapore 138648, Singapore.
Theodore L. Roth
1Biomedical Sciences Graduate Program, University of California, San Francisco (UCSF), San Francisco, CA 94143, USA.
3Department of Microbiology and Immunology, UCSF, San Francisco, CA 94143, USA.
4Diabetes Center, UCSF, San Francisco, CA 94143, USA.
Ventura F. Mendoza
5Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, CA 94143, USA.
Alexander Marson
3Department of Microbiology and Immunology, UCSF, San Francisco, CA 94143, USA.
4Diabetes Center, UCSF, San Francisco, CA 94143, USA.
6Innovative Genomics Institute, University of California, Berkeley, CA 94720, USA.
7Department of Medicine, UCSF, San Francisco, CA 94143, USA.
8Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
9UCSF Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA 94158, USA.
10Parker Institute for Cancer Immunotherapy, San Francisco, CA 94129, USA.
Trevor D. Burt
5Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, CA 94143, USA.
11Department of Pediatrics, Division of Neonatology, UCSF, San Francisco, CA 94110, USA.
