Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles

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Science Immunology  01 Nov 2019:
Vol. 4, Issue 41, eaay6125
DOI: 10.1126/sciimmunol.aay6125

Article Information

vol. 4 no. 41

Published By: 
  • Received July 3, 2019
  • Accepted October 1, 2019
  • .

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Author Information

  1. Velislava N. Petrova1,*,
  2. Bevan Sawatsky2,
  3. Alvin X. Han3,4,
  4. Brigitta M. Laksono5,
  5. Lisa Walz2,,
  6. Edyth Parker4,
  7. Kathrin Pieper6,
  8. Carl A. Anderson1,
  9. Rory D. de Vries5,
  10. Antonio Lanzavecchia6,
  11. Paul Kellam7,8,,
  12. Veronika von Messling2,,§,
  13. Rik L. de Swart5, and
  14. Colin A. Russell4,,*
  1. 1Department of Human Genetics, Wellcome Sanger Institute, Cambridge, UK.
  2. 2Veterinary Medicine Division, Paul-Ehrlich-Institut, Federal Institute for Vaccines and Biomedicines and DZIF TTU Emerging Infections, Langen, Germany.
  3. 3Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
  4. 4Laboratory of Applied Evolutionary Biology, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  5. 5Department of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands.
  6. 6Institute for Research in Biomedicine, Università della Svizzera Italiana, Bellinzona, Switzerland.
  7. 7Department of Medicine, Division of Infectious Diseases, Imperial College Faculty of Medicine, Wright Fleming Institute, St Mary’s Campus, London, UK.
  8. 8Kymab Ltd., The Bennet Building, Babraham Research Campus, Cambridge, UK.
  1. *Corresponding author. Email: vp5{at} (V.N.P.); c.a.russell{at} (C.A.R.)
  • Present address: CureVac AG, Schumannstrasse 27, 60325 Frankfurt, Germany.

  • These authors contributed equally to this work.

  • § Present address: Life Science Division, German Federal Ministry of Education and Research, Kapelle-Ufer 1, Berlin, Germany.


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