FocusTUMOR IMMUNOLOGY

A new perspective in cancer immunotherapy: PD-1 on myeloid cells takes center stage in orchestrating immune checkpoint blockade

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Science Immunology  03 Jan 2020:
Vol. 5, Issue 43, eaaz8128
DOI: 10.1126/sciimmunol.aaz8128

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Abstract

PD-1 mediates antitumor immunity by regulating lineage fate commitment and function of myeloid cells (see the related Research Article by Strauss et al.).

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