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Tumor neoantigenicity assessment with CSiN score incorporates clonality and immunogenicity to predict immunotherapy outcomes

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Science Immunology  21 Feb 2020:
Vol. 5, Issue 44, eaaz3199
DOI: 10.1126/sciimmunol.aaz3199

Article Information

vol. 5 no. 44

PubMed: 
Published By: 
History: 
  • Received August 29, 2019
  • Revision received November 11, 2019
  • Accepted January 30, 2020
  • .

Author Information

  1. Tianshi Lu1,
  2. Shidan Wang1,
  3. Lin Xu1,2,
  4. Qinbo Zhou1,
  5. Nirmish Singla3,4,
  6. Jianjun Gao5,
  7. Subrata Manna6,
  8. Laurentiu Pop6,
  9. Zhiqun Xie1,
  10. Mingyi Chen7,
  11. Jason J. Luke8,
  12. James Brugarolas4,9,
  13. Raquibul Hannan4,6 and
  14. Tao Wang1,4,*
  1. 1Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Division of Hematology/Oncology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  4. 4Kidney Cancer Program, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  5. 5Department of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  6. 6Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  7. 7Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  8. 8University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
  9. 9Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
  1. *Corresponding author. Email: tao.wang{at}utsouthwestern.edu

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Article usage: February 2020 to January 2021

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Feb 2020191114921779
Mar 20209381272308
Apr 20205477246
May 20203525921
Jun 20202442926
Jul 2020239157
Aug 20205984923
Sep 20201495322
Oct 2020149408
Nov 20201383313
Dec 20201166421
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