March 2020
Vol 5, Issue 45

About The Cover

Cover image expansion

ONLINE COVER Tracing Peanut IgE Emergence. This month's cover shows the edible seeds of Arachis hypogaea, the legume responsible for many cases of human food allergy. In this issue, Hoh et al. apply immunoglobulin heavy chain sequencing to gut tissue biopsies from peanut allergic patients to search for the underlying pathogenesis of symptomatic IgE-mediated food allergies. A Perspective commentary by Wesemann and Nagler in Science discusses the findings of Hoh et al. [CREDIT: HEKLA/SHUTTERSTOCK]