Absence of MHC class II on cDC1 dendritic cells triggers fatal autoimmunity to a cross-presented self-antigen

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  Absence of MHC class II on cDC1 dendritic cells triggers fatal autoimmunity to a cross-presented self-antigen

  By Christian Wohn, Valentin Le Guen, Odessa Voluzan, Frédéric Fiore, Sandrine Henri, Bernard Malissen

  Science Immunology13 Mar 2020

  Wohn et al. demonstrate that cDC1 cross-tolerizing capacity requires MHCII-restricted interaction with regulatory T cells.

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  Absence of MHC class II on cDC1 dendritic cells triggers fatal autoimmunity to a cross-presented self-antigen

  By Christian Wohn, Valentin Le Guen, Odessa Voluzan, Frédéric Fiore, Sandrine Henri, Bernard Malissen

  Science Immunology13 Mar 2020

  Wohn et al. demonstrate that cDC1 cross-tolerizing capacity requires MHCII-restricted interaction with regulatory T cells.

  • Supplementary Materials

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