Research ArticleMALARIA

Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria

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Science Immunology  26 Jun 2020:
Vol. 5, Issue 48, eaaz8035
DOI: 10.1126/sciimmunol.aaz8035

Article Information

vol. 5 no. 48

PubMed: 
Published By: 
History: 
  • Received October 28, 2019
  • Accepted May 22, 2020
  • .

Author Information

  1. Lauren E. Holz1,2,*,
  2. Yu Cheng Chua1,*,
  3. Maria N. de Menezes1,
  4. Regan J. Anderson3,
  5. Sarah L. Draper3,
  6. Benjamin J. Compton3,
  7. Susanna T. S. Chan3,
  8. Juby Mathew3,
  9. Jasmine Li4,
  10. Lukasz Kedzierski1,5,
  11. Zhongfang Wang1,
  12. Lynette Beattie1,2,
  13. Matthias H. Enders1,2,6,
  14. Sonia Ghilas1,2,
  15. Rose May1,
  16. Thiago M. Steiner1,2,
  17. Joshua Lange7,
  18. Daniel Fernandez-Ruiz1,
  19. Ana Maria Valencia-Hernandez1,8,
  20. Taryn L. Osmond7,9,
  21. Kathryn J. Farrand7,
  22. Rebecca Seneviratna1,
  23. Catarina F. Almeida1,2,
  24. Kirsteen M. Tullett10,
  25. Patrick Bertolino11,
  26. David G. Bowen11,
  27. Anton Cozijnsen12,
  28. Vanessa Mollard12,
  29. Geoffrey I. McFadden12,
  30. Irina Caminschi10,
  31. Mireille H. Lahoud10,
  32. Katherine Kedzierska1,
  33. Stephen J. Turner4,
  34. Dale I. Godfrey1,2,
  35. Ian F. Hermans7,9,13,,
  36. Gavin F. Painter3,9,, and
  37. William R. Heath1,2,,
  1. 1Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
  2. 2Australian Research Council Centre of Excellence in Advanced Molecular Imaging, University of Melbourne, Melbourne, VIC, Australia.
  3. 3Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand.
  4. 4Department of Microbiology, Biomedical Discovery Institute, Monash University, Clayton, VIC, Australia.
  5. 5Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Melbourne, VIC, Australia.
  6. 6LIMES Institute, University of Bonn, Bonn, Germany.
  7. 7Malaghan Institute of Medical Research, Wellington, New Zealand.
  8. 8Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  9. 9Avalia Immunotherapies Limited, Lower Hutt, New Zealand.
  10. 10Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.
  11. 11Centenary Institute, The University of Sydney and AW Morrow Gastroenterology and Liver Centre, Liver Immunology Program, Newtown, NSW, Australia.
  12. 12School of BioSciences, University of Melbourne, Parkville, VIC, Australia.
  13. 13Maurice Wilkins Centre for Molecular Biodiscovery, Wellington, New Zealand.
  1. Corresponding author. Email: wrheath{at}unimelb.edu.au (W.R.H.); gavin.painter{at}vuw.ac.nz (G.F.P.)
  • * These authors contributed equally to this work as co-first authors.

  • These authors contributed equally to this work as co-senior authors.

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