Research ArticleCORONAVIRUS

The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

See allHide authors and affiliations

Science Immunology  11 Jun 2020:
Vol. 5, Issue 48, eabc8413
DOI: 10.1126/sciimmunol.abc8413

Article Information

vol. 5 no. 48

PubMed: 
Published By: 
History: 
  • Received May 16, 2020
  • Accepted June 9, 2020
  • .

Article Versions

Author Information

  1. Lakshmanane Premkumar1,*,
  2. Bruno Segovia-Chumbez1,
  3. Ramesh Jadi1,
  4. David R. Martinez2,
  5. Rajendra Raut1,
  6. Alena J. Markmann3,
  7. Caleb Cornaby4,
  8. Luther Bartelt3,
  9. Susan Weiss3,
  10. Yara Park3,
  11. Caitlin E. Edwards2,
  12. Eric Weimer5,
  13. Erin M. Scherer6,
  14. Nadine Rouphael6,
  15. Srilatha Edupuganti6,
  16. Daniela Weiskopf7,
  17. Longping V. Tse2,
  18. Yixuan J. Hou2,
  19. David Margolis1,2,3,
  20. Alessandro Sette7,8,
  21. Matthew H. Collins6,
  22. John Schmitz5,
  23. Ralph S. Baric1,2 and
  24. Aravinda M. de Silva1,*
  1. 1Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  2. 2Department of Epidemiology, UNC Chapel Hill School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  3. 3Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  4. 4Immunology/Histocompatibility and Immunogenetics Laboratories, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  5. 5Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
  6. 6Hope Clinic of the Emory Vaccine Center, Division of Infectious Diseases, Department of Medicine, School of Medicine, Emory University, Decatur, GA 30322, USA.
  7. 7Center for Infectious Disease and Vaccine Research, Institute for Immunology (LJI), La Jolla, La Jolla, CA 92037, USA.
  8. 8Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego (UCSD), La Jolla, CA 92037, USA.
  1. *Corresponding author. Email: prem{at}med.unc.edu (L.P.); aravinda_desilva{at}med.unc.edu (A.M.d.S.)

Altmetric

Article usage

Article usage: June 2020 to July 2020

AbstractFullPdf
Jun 2020486277397027
Jul 2020502130594

Stay Connected to Science Immunology

Navigate This Article