Shed it, and help—LAG3 cleavage drives conventional CD4+ T cells to overcome resistance to PD-1 immunotherapy

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Science Immunology  17 Jul 2020:
Vol. 5, Issue 49, eabc8644
DOI: 10.1126/sciimmunol.abc8644

Article Information

vol. 5 no. 49

Published By: 
  • Received June 10, 2020
  • Accepted June 23, 2020
  • .

Author Information

  1. Lea Seidel1,2,3,4 and
  2. Bertram Bengsch1,2,*
  1. 1Faculty of Medicine, Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Disease, University Medical Center Freiburg, Freiburg, Germany.
  2. 2Signaling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.
  3. 3SGBM - Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany.
  4. 4Faculty of Biology, University of Freiburg, Freiburg, Germany.
  1. *Corresponding author. Email: bertram.bengsch{at}


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Article usage: July 2020 to August 2020

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